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How Long Do Opioids Stay in Your System?

girl wondering how long opioids stay in your systemm

Understanding the persistence of opioids in the body is crucial for effective treatment and support. From the moment opioids are ingested to when they begin to metabolize and eliminate, various factors come into play that influence how long they linger in the system. Today we discuss the dynamics of opioid presence in the body, discuss how long do opioids stay in your system, and offer insights into how Serenity Grove can assist those in need.

Opioids are a class of drugs that include prescription painkillers like oxycodone and morphine, as well as illegal drugs like heroin and fentanyl. They are notorious for their addictive potential and impact on the body. In 2021, over 106,000 people died from drug overdoses, and almost 80% of those deaths were linked to opioids. As individuals navigate the complexities of addiction and recovery, knowing the duration of opioids in their system is essential for seeking appropriate assistance.

If you or a loved one is struggling with opioid use disorder, call Serenity Grove today at 844-904-3485. Our opioid addiction treatment program in Georgia can help you find the change needed to create long-term recovery.

How Long Do Opioids Stay in Your System?

The duration opioids remain detectable in the body varies depending on several factors, including the type of opioid consumed, individual metabolism, frequency of use, and dosage. Different opioids have distinct half-lives, which determine how long it takes for half of the drug to be eliminated from the body.

Factors such as liver function, kidney function, hydration levels, body mass index (BMI), overall health and genetics also influence the metabolism and elimination of opioids. For instance, opioids may linger longer in the system of individuals with impaired liver or kidney function.

On average, here’s a breakdown of how long various opioids can be detected in the body via different testing methods:


Urine: 1-3 days

Blood: 3-6 days

Hair: Up to 90 days


Urine: 1-2 days

Blood: 6-72 hours

Hair: Up to 90 days


Urine: 3-5 days

Blood: 12-72 hours

Hair: Up to 90 days


Urine: 1-2 days

Blood: 12-24 hours

Hair: Up to 90 days


Urine: 2-3 days

Blood: 12-24 hours

Hair: Up to 90 days

It’s important to emphasize that these provided estimates are general guidelines. The actual duration of opioids staying in your system can vary significantly based on various factors, as mentioned earlier. 

The Half-Life of Opioids

The half-life of a drug refers to the amount of time it takes for the body to remove fifty percent of the drug from its system. For example:

Heroin: Heroin has a short half-life of only about 8-22 minutes. Due to its short half-life, it can lead to individuals taking more heroin to maintain their high, thus leading to a greater number of overdoses.

Morphine: Morphine, a naturally occurring opioid, has a half-life ranging from 2 to 4 hours.

Oxycodone: Oxycodone, commonly found in prescription pain medications, has a half-life of approximately 4.5 to 6.5 hours.

Fentanyl: Fentanyl, a potent synthetic opioid, has a long half-life of about 8 to 10 hours.

Knowing the half-life of a drug is important for understanding how long it affects you. But keep in mind, the half-life doesn’t always match up with how long it shows up in drug tests. If you have a drug test coming soon, it’s good to know how long the drug stays in your body, especially in urine.

How Long Will Opioids Show Up on a Drug Test?

The detection window for opioids varies depending on the type of drug test used and the opioid in question. Commonly employed drug tests include urine, blood, saliva, and hair tests, with urine tests being the most commonly used method.

Urine Test: Opioids can typically be detected in urine for 2 to 4 days after the last use, although this window may be longer for chronic users or certain opioids.

Blood Test: Opioids are detectable in the bloodstream for a shorter period, usually up to 12 hours after the last use.

Saliva Test: Saliva tests can detect opioids for up to 1 to 4 days following use.

Hair Test: Hair follicle tests have the longest detection window, with opioids detectable for up to 90 days.

Find Opioid Treatment in Georgia Today

In conclusion, the duration opioids stay in your system can vary significantly, influenced by factors such as drug type, metabolism, and testing method. By understanding these dynamics and seeking support from trusted resources like Serenity Grove, individuals can embark on a journey toward recovery and renewed well-being. Our compassionate team offers comprehensive addiction treatment programs tailored to individual needs. Whether you’re seeking detoxification, counseling, or ongoing support, we’re here to guide you toward a life of sobriety and fulfillment.

If you or a loved one is struggling with opioid addiction, don’t hesitate to reach out to Serenity Grove. Our experienced professionals are dedicated to helping you reclaim your life and embrace a future free from the grip of addiction.